Prof Cardaci is a Nuclear Medicine Physician with a long-standing interest in theranostics. He was involved in the early development of SIRT therapy for liver cancer. He has been involved in multiple international research trials advancing the field of radionuclide therapy in advanced malignancies. Dr Cardaci's clinical interests are advanced prostate cancer, neuroendocrine tumours (NETs), and liver cancer.

Prof Cardaci also practices as a General Medicine Physician, overseeing a busy medical department at Hollywood Private Hospital, Perth. He is actively engaged in medical student and Basic Physician training, and is Adjunct Associate Professor at University of Notre Dame